EpiSAMe Supplements


epiSAM-e (S-Adenosyl-L-Methionine), 400 mg, 60 Enteric-Coated Caplets

*Exclusive  offer – Only $24 for up to 6 Supplements when purchased together with the Kit.

SKU: 679628580012 Category:


epiSAMe (S-Adenosyl-L-Methionine).

Active Ingredients.

  • pH-Sensitive
  • S-Adenosyl Methionine
  • 400 mg (Net Yield) SAM-e from 800 mg
  • b-80%+ active (S,S) isomer
  • SAM-e tosylate Disulfate
  • Highest Concentration of Active S,S Form

*Food Grade, Dairy-Free, No Preservatives, Allergen-Free, No Yeast or Gluten, Kosher Certified

What is epiSAMe?

S-adenosyl-L-methionine (SAMe), is a natural compound found in the body that helps produce and regulate hormones and maintain cell membranes. It is considered the most important methyl donor in the body, which has been shown in clinical studies to improve mood & emotional well-being. While SAMe also improves joint health, comfort, mobility, and healthy liver function.

The level of epiSAMe decreases as the body ages. Concomitantly, a number of health issues, including mood, joined, and liver disorders are likely to occur​.

All SAM-e molecules have two forms: the SS (active) isomer and the RS (inactive) isomer.

While epiSAMe comes in two stable salt forms; tosylate and butane disulphonate, only the tosylate form is backed by twenty years of research for safety and effectiveness.

Why Chose epiSAMe

  • Manufactured to the highest standards, using the original
    Italian method (salt - tosylate disulfate)
  • SAMe products’ starting raw materials consistently
    test at the highest SS to RS isomer ratio on the market:
    SS isomer >80% / RS isomer <20%.
  • Enteric coated for optimum absorption by the body
  • Sealed in blister packs to ensure freshness
  • Made to guaranteed purity and potency standards:No Artifical Flavors, Dairy Free, No Preservatives,
    Allergen Free, No Yeast or Gluten, Kosher Certified
  • Have been tested for a minimum full two year stability rating
  • Feed us with your health and lifestyle information
    to establish your personalized health ecosystem

In the Spotlight


From the literature:

SAM-e has been shown to improve mood & emotional well being, joint health, comfort & mobility and healthy liver function in clinical studies.

In March of 2003, the AHRQ (Agency for Healthcare Research and Quality) a division of the United States Health and Human Services, released the findings of a major study on SAM-e.

SAM-e is as effective as conventional prescription medications in the treatment of depression.

SAM-e is as effective as standard prescription medications (NSAIDs) in the treatment of osteoarthritis.

SAM-e has significant benefits for patients suffering from various liver diseases. Natural SAM-e was not found to have any noticeable side effects.

Basic research on SAM-e on human cell lines and animals which were not yet followed by clinical studies